That's why many nutritionists recommend a little protein with your breakfast. This is one of the most powerful ways to treat the symptoms of inflammation and relieve pain. Use Ibuprofen or other over-the-counter pain relievers. This is when the piriformis muscle expands from the sacrum's side to the top most portion of the thigh bone located at the hip joint while it passes over the route of the sciatic nerve. Nerve Defend can help you a lot and protect you from chronic nerve pain.